This assignment focuses on Sexually Transmitted Infections and the pathogenesis of Neisseria gonorrhoeae. The most common site of Neisseria gonorrhoeae infection is the urogenital tract. Men with this infection may have penile discharge. Women may experience vaginal mucopurulent discharge and severe pelvic pain. Other common Neisseria gonorrhoeae infections are anorectal, pharyngeal, conjunctival, and uterine infections. Untreated infections can spread to other areas of the body, causing skin and joint infections. Commonly infected joints include ankles, wrists, and the joints of the feet and hands. In severe cases, patients can get gonococcal infections and meningitis. Medical professionals use culture and nonculture tests to detect Neisseria gonorrhoeae infections.
Sexually Transmitted Infections (STIs) and pathogenesis of Neisseria gonorrhoeae
HOST ADAPTATION AND PATHOGENESIS OF NEISSERIA GONORRHOEAE
This section provides the details of the pathogenesis of Neisseria gonorrhoeae. The stages of pathogenesis include transmission, adherence, colonization and invasion, and immune evasion. It has several virulence factors that promote its survival and replication. Neisseria gonorrhoeae infections may, therefore, become more severe owing to it’s the bacteria’s natural competence. It is necessary to understand the mechanisms by which resistance determinants confer resistance in finding treatments for Sexually Transmitted Infections (STIs). Professionals in the field are also working to develop novel therapies to avoid an era of untreatable gonorrhea. Advancements in standardizing cell culture techniques of primary tissue culture and transgenic mouse models help to counter these challenges.
host adaptation and pathogenesis of Neisseria gonorrhoeae
GONORRHEA AND OTHER SEXUALLY TRANSMITTED INFECTIONS
Apart from the pathogenesis of Neisseria gonorrhoeae, there are many other STIs. They include chlamydia, genital herpes, and genital warts. In gonorrhea, the bacterium infects the mucous membranes of the reproductive tract, including the urethra, cervix, uterus, and fallopian tubes. Neisseria gonorrhoeae infections occur in the mucous membranes of the mouth, throat, eyes, and rectum. In the U.S., gonorrhea is common in young adults, with more than 500,000 cases in 2018. In Australia, the most common Sexually Transmitted Infection (STI) is chlamydia. The bacterium Chlamydia trachomatis causes it. Genital herpes, caused by the herpes simplex virus (HSV), results in sores and blisters on the genitals.
gonorrhea and other STIs
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