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THE RISK FACTORS OF RCVS AND TREATMENT OF RCVS

This thesis describes the risk factors of RCVS and the treatment of RCVS. Reversible cerebral vasoconstriction syndrome (RCVS) is a group of disorders characterized by multifocal narrowing of the cerebral arteries and severe headaches. RCVS happens when the vasoconstriction of the blood vessel causes arteries to narrow, reducing blood flow and oxygen delivery to the affected area of the body. The cause of RCVS is unknown. However, the risk factors of RCVS are conditions that increase the chances of developing the disease. The latter includes a history of migraines and the misuse of drugs. The symptoms of RCVS are “thunderclap” headache and seizures. Notably, there are complications of RCVS, such as brain edema and strokes. Fortunately, there are measures for the treatment of RCVS.

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THE COMPLICATIONS AND RISK FACTORS OF RCVS

The risk factors of RCVS consists of biological and genetic conditions. They include complications of pregnancy (eclampsia and pre-eclampsia) or changing birth control pills postpartum. Therefore, women between the ages of 20 to 50 are at higher risk of developing the disease than men. Also, having a history of migraine, Use of certain prescription medications, such as anti-depressants, Use of nasal decongestants, and illicit drug use like alcohol and nicotine can increase the chances of developing the disease. Lastly, other risk factors are underlying conditions like head trauma, hyperkalemia, and cervical artery dissection. Notably, the complications of RCVS include cerebral vasoconstriction, brain edema, and strokes, which can result in severe disability and even death. Thus, early diagnosis is vital for the treatment of RCVS.

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THE PREVENTION AND TREATMENT OF RCVS

Treatment of RCVS depends on the severity of the condition. For instance, calcium channel blockers such as verapamil and nimodipine may relax the blood vessels and allow more blood to flow through. Thus, these medications may help reduce the intensity and frequency of the “thunderclap” headaches but do not decrease the risk of stroke. Secondly, migraine treatments include medicines, such as aspirin or Depakote. Thirdly, avoiding some of the risk factors of RCVS, such as vasoactive drugs, can help one manage symptoms. Fourthly, analgesics, and anticonvulsants can help manage pain and seizures, respectively. Lastly, high-dose corticosteroids may prevent some of the complications of RCVS, such as subarachnoid hemorrhage. In conclusion, the treatment of RCVS is currently based on expert opinion and reported case series.

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